2021 Iowa State Cyclones Football Betting Odds & Predictions

Sportsbooks for US players know that after finishing short last season, the Cyclones aim to set a franchise record with their first 10-win season. Two Heisman hopefuls, 19 of their 21 starters return, and three-time Big-12 Coach of the Year Matt Campell. Iowa State has a lot to look forward to.

Our preseason best bet is Iowa State to win the Big 12 Championship at +225 on the best online sportsbooks. Choosing between that and over 9.5 wins is hard. With so much talent returning from last year’s 9-3 season it’s tough to see this team as anything other than a serious contender. Campbell has turned this program into a force to be reckoned with. There’s a reason they have nine wins against ranked opponents since 2017.

PRESEASON BEST BET: WIN BIG 12 CHAMPIONSHIP +225

2021 IOWA STATE CYCLONES SCHEDULE

  • 09/04/2021 – vs. UNI 09/11/2021 – vs. Iowa
  • 09/18/2021 – at UNLV
  • 09/25/2021 – at Baylor
  • 10/02/2021 – vs. Kansas
  • 10/16/2021 – ar Kansas State
  • 10/23/2021 – vs. Oklahoma State
  • 10/30/2021 – at West Virginia
  • 11/06/2021 – vs. Texas
  • 11/13/2021 – at Texas Tech
  • 11/20/2021 – at Oklahoma
  • 11/26/2021 – vs. TCU

WIN TOTAL ODDS Over 9.5 -113 Under 9.5 -113

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IOWA STATE ODDS TO WIN 2021 BIG 12 CHAMPIONSHIP +225

Quarterback Brock Purdy and coach Campbell both turned down NFL offers. It’s clear this program has championship goals. The Cyclones get to flex their talented tight ends, such as Charlie Kolar who is arguably the best tight end in the nation. Purdy will not only have several weapons to rely on but the team’s defense has limited Oklahoma to their lowest points total in three of the last four seasons.

2021 IOWA STATE ODDS TO WIN 2021-22 COLLEGE FOOTBALL PLAYOFF +3300

At +3300 on sportsbooks for US players it’s definitely worth a shot, but competing with National Championship candidate Oklahoma is a tall order. They’ll have to do it several times. Even with all the returning talent, it’s not a given they have the same ceiling as Oklahoma, Alabama, or Clemson.

IOWA STATE 2021 HEISMAN CONTENDERS and ODDS

CONTENDERS Odds
BREECE HALL  +4000
BROCK PURDY  +5000

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Hall is one of the best running backs in college football. Considering the low percentage of running backs who have won this award in the last 20 years, it’s a hard pass. When running backs can climb that mountain and win the Heisman it usually comes down to playing at schools that dominate the media, which Iowa State is not.

Great running back but not crazy about the odds at sportsbooks for US players. Brock Purdy will most likely finish this season as Iowa States’ best QB ever. He’s done great things for this program and has been crucial to their success. But he lacks the media attention to compete with some of the other guys on the list. He’s a great QB who will have another great season, and that’s about it.

2020 IOWA STATE CYCLONES BETTING RESULTS

  • 09/12/2020 – Louisiana 31 (+13) at Iowa State 14 – Under, 56.5
  • 09/26/2020 – Iowa State 37 at TCU 34 (+4.5) – Over, 43
  • 10/03/2020 – Oklahoma 30 at Iowa State 37 (+7.5) – Over, 62.5
  • 10/10/2020 – Texas Tech 15 at Iowa State 31 (-10) – Under, 63
  • 10/24/2020 – Iowa State 21 at Oklahoma State 24 (-2.5) – Under, 54
  • 10/31/2020 – Iowa State 52 (-27.5) at Kansas 22 – Over, 49.5
  • 11/07/2020 – Baylor 31 (+14) at Iowa State 38 – Over, 47
  • 11/21/2020 – Kansas State 0 at Iowa State 45 (-13.5) – Under, 48
  • 11/27/2020 – Iowa State 23 (-1.5) at Texas 20 – Under, 57.5
  • 12/05/2020 – West Virginia 6 at Iowa State 42 (-6) – Push, 48
  • 12/19/2020 – Oklahoma 27 (-5.5) at Iowa State 21 – Under, 59.5
  • 01/02/2021 – Oregon 17 at Iowa State 34 (-4.5) – Under, 57.5